The gut microbiome significantly impacts ageing, with microbial composition shaping healthspan and longevity. Microbiome-targeted interventions hold promise for promoting healthy ageing and extending lifespan.
October 2024 – Science Direct
Key Takeaways
- Gut microbiome composition plays a crucial role in shaping healthspan and longevity: The gut microbiome, a diverse ecosystem of bacteria, fungi, and other microorganisms, significantly influences overall health. The specific types and balance of these microbes can impact the body’s inflammation levels, immune function, and cellular repair, all of which are directly linked to ageing processes and healthspan
- Microbiome-targeted therapies have the potential to delay ageing processes and enhance lifespan: Therapies aimed at modifying the gut microbiome, such as prebiotics, probiotics, and even faecal transplants, show promising effects on slowing age-related decline. By optimising the gut’s microbial balance, these approaches can help support metabolic health, reduce age-related inflammation, and possibly extend longevity
- A balanced and diverse gut microbiome supports better immune function and metabolic health, both vital for ageing well: A healthy gut microbiome contributes to a robust immune system and efficient metabolism, both critical to maintaining vitality in later years. It helps prevent infections, promotes nutrient absorption, and regulates blood sugar, collectively enhancing resilience against age-related illnesses and supporting healthy ageing
Diets rich in fibre, antioxidants, and diverse plant-based foods encourage a healthy microbiome, while avoiding excessive sugar and processed foods protects microbial balance. Regular physical activity and stress management further promote microbiome health, making lifestyle changes a practical approach to supporting longevity and healthier ageing.
Read the article at: Marth, T., et al. “The Gut Microbiome’s Role in Ageing and Longevity.” Mechanisms of Ageing and Development, vol. 216, 2024, DOI: 10.1016/j.mad.2024.111056.