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Rejuvenation with young vesicles

Aug 7, 2023

Young extracellular vesicles show promise in reversing age-related deterioration in elderly rats and human cellular models, hinting at innovative anti-ageing treatments.

July 2023 – Scientific Reports

 

Key takeaways

 

  • Young extracellular vesicles promote rejuvenation: The study suggests that extracellular vesicles derived from young organisms can rejuvenate older organisms, potentially leading to improved health and longevity
  • Improvement in cognitive functions: There is evidence that these young extracellular vesicles can enhance cognitive functions in aged individuals, which could have implications for age-related cognitive decline
  • Potential for tissue repair and regeneration: Young extracellular vesicles may have the ability to facilitate tissue repair and regeneration, offering a promising avenue for reversing age-related tissue degeneration
  • Influence on longevity-related biomarkers: The study points to the possibility that young extracellular vesicles can alter biomarkers associated with ageing, suggesting a potential for these vesicles to be used as a therapeutic strategy for extending healthy lifespan

 

The study’s findings are a significant step in longevity research, offering a glimpse into a future where ageing could be tackled at the cellular level. It raises the questions; how might vesicle therapy change the landscape of regenerative medicine? and what implications do altered ageing biomarkers have for the future of longevity?

 

Read the paper at: Grigorian Shamagian, L., Rogers, R.G., Luther, K. et al. Rejuvenating effects of young extracellular vesicles in aged rats and in cellular models of human senescence. Sci Rep 13, 12240 (2023). https://doi.org/10.1038/s41598-023-39370-5