ADVANCED HEALTH TESTING
Methylation test Australia
MTHFR, COMT, AHCY, MTRR, CBS, MTR, PEMT, MTHFD1, Choline, Betaine and B vitamins
Australia’s best methylation test to discover your genetic methylation status, and if you need to pay extra care to nutritional and lifestyle factors to optimise your methylation effectiveness.


Introducing the MyDNA comprehensive genetics test for methylation
Your genes are like the hand of cards you’ve been dealt, and while you can’t change them, knowing what you’ve been dealt goes a long way in helping you play a better game, for life.
Rather than focus on disease risk, this test empowers you with information on how nutrient deficiency or toxicity may play a role in affecting gene function, including methylation, why certain health disorders may run in your family, and what you can actively do now to decrease the probability of disease through the application of diet, lifestyle and exercise to adjust the expression of these genes. This is an empowering test that analyses your base genetic blueprint. It is a starting point so that you can identify potential weaknesses and then learn of various ways to epigenetically improve them.
Introducing the MyDNA comprehensive genetics test for methylation
Your genes are like the hand of cards you’ve been dealt, and while you can’t change them, knowing what you’ve been dealt goes a long way in helping you play a better game, for life.
Rather than focus on disease risk, this test empowers you with information on how nutrient deficiency or toxicity may play a role in affecting gene function, including methylation, why certain health disorders may run in your family, and what you can actively do now to decrease the probability of disease through the application of diet, lifestyle and exercise to adjust the expression of these genes. This is an empowering test that analyses your base genetic blueprint. It is a starting point so that you can identify potential weaknesses and then learn of various ways to epigenetically improve them.


Why should I do a genetic methylation test?
A genetic methylation test identifies single nucleotide polymorphisms (SNPs) that may impair methylation, a process critical for numerous bodily functions. By pinpointing genetic variations, such as those in the MTHFR, MTR, MTRR, COMT, CBS, PEMT, and MTHFD1 genes, the test provides valuable insights for personalised nutritional support to enhance methylation efficiency.
For instance, MTHFR affects folate metabolism, and its variants can lead to folate deficiency or elevated homocysteine levels, increasing the risk of cardiovascular issues. MTR and MTRR impact the conversion of homocysteine into methionine, with variants linked to higher homocysteine levels and associated health risks, like heart disease and dementia. The COMT gene influences neurotransmitter metabolism, and its variations may contribute to mood and behavioural disorders.
By addressing these genetic factors with targeted dietary and supplement strategies, individuals can support optimal methylation, potentially reducing the risk of chronic illnesses and improving overall health.

Why should I do a genetic methylation test?
A genetic methylation test identifies single nucleotide polymorphisms (SNPs) that may impair methylation, a process critical for numerous bodily functions. By pinpointing genetic variations, such as those in the MTHFR, MTR, MTRR, and COMT genes, the test provides valuable insights for personalised nutritional support to enhance methylation efficiency.
For instance, MTHFR affects folate metabolism, and its variants can lead to folate deficiency or elevated homocysteine levels, increasing the risk of cardiovascular issues. MTR and MTRR impact the conversion of homocysteine into methionine, with variants linked to higher homocysteine levels and associated health risks, like heart disease and dementia. The COMT gene influences neurotransmitter metabolism, and its variations may contribute to mood and behavioural disorders.
By addressing these genetic factors with targeted dietary and supplement strategies, individuals can support optimal methylation, potentially reducing the risk of chronic illnesses and improving overall health.

Why we recommend this genetic methylation test
We’ve explored various DNA tests, and this one stands out for its depth, specificity, and actionable insights – far surpassing most others on the market.
Rather than simply focusing on disease risks, this test empowers you with clear, practical steps to optimise your health now and safeguard it for the future. It’s about creating health, not just analysing potential issues.
For added peace of mind, your DNA is processed exclusively in a certified Australian laboratory, ensuring both accuracy and security. This means you can move forward confidently, equipped with valuable insights and a personalised plan for vibrant health.
Why we recommend this genetic methylation test
We’ve explored various DNA tests, and this one stands out for its depth, specificity, and actionable insights – far surpassing most others on the market.
Rather than simply focusing on disease risks, this test empowers you with clear, practical steps to optimise your health now and safeguard it for the future. It’s about creating health, not just analysing potential issues.
For added peace of mind, your DNA is processed exclusively in a certified Australian laboratory, ensuring both accuracy and security. This means you can move forward confidently, equipped with valuable insights and a personalised plan for vibrant health.


About the lab
MyDNA Life was the first clinical genetics company in Australia, founded by Associate Professor Leslie Sheffield and your DNA is processed in their state of the art, NATA accredited, CLIA and CAP certified, DNA analysis laboratory. Samples are run on parallel arrays including Next Generation Sequencing technology for extremely accurate results.
Thanks to operating to these rigorous standards, the laboratory achieves 99.9% results accuracy. Data privacy is of utmost importance so your data is stored on secure, encrypted servers, can’t be used to identify you, will never be shared with third parties without your consent, and has no bearing on insurance policies or premiums. MyDNA Life chooses NATA and CLIA accredited NutriPATH to deliver their practitioner only services.

About the lab
MyDNA Life was the first clinical genetics company in Australia, founded by Associate Professor Leslie Sheffield and your DNA is processed in their state of the art, NATA accredited, CLIA and CAP certified, DNA analysis laboratory. Samples are run on parallel arrays including Next Generation Sequencing technology for extremely accurate results.
Thanks to operating to these rigorous standards, the laboratory achieves 99.9% results accuracy. Data privacy is of utmost importance so your data is stored on secure, encrypted servers, can’t be used to identify you, will never be shared with third parties without your consent, and has no bearing on insurance policies or premiums. MyDNA Life chooses NATA and CLIA accredited NutriPATH to deliver their practitioner only services.

Why choose Melbourne Functional Medicine
At Melbourne Functional Medicine, your health is in the hands of experienced functional medicine practitioners who have reviewed thousands of functional pathology reports and standard blood panels.
With deep expertise in human physiology and biochemistry, our team interprets your results to uncover what’s really going on in your body - and what to do about it. We don’t just hand you numbers. We help you make sense of them, so you can personalise your health protocols based on real data.
We also understand that results can sometimes feel confronting. That’s why we’re here to guide you through them with compassion, clarity, and a focus on solutions - empowering you to take confident, informed steps towards better health.
Why choose Melbourne Functional Medicine
At Melbourne Functional Medicine, your health is in the hands of experienced functional medicine practitioners who have reviewed thousands of functional pathology reports and standard blood panels.
With deep expertise in human physiology and biochemistry, our team interprets your results to uncover what’s really going on in your body - and what to do about it. We don’t just hand you numbers. We help you make sense of them, so you can personalise your health protocols based on real data.
We also understand that results can sometimes feel confronting. That’s why we’re here to guide you through them with compassion, clarity, and a focus on solutions - empowering you to take confident, informed steps towards better health.

Frequently
Asked
Questions
How do I order this genetic methylation test?
Contact us at [email protected] or 1300 614 814, so we can ensure this is the right test for you, then we’ll set you up as a patient, order and despatch a test kit to your nominated address. You’ll follow the instructions to take your sample and post back
We’ll let you know once your test results are back, to make sense of the report which provides a 100+ page report. We highly recommend a Test Interpretation Session.
Is this methylation test for me?
This test is for you if:
- You want to play a proactive role in your health outcomes
- You are curious to know why certain diseases run in your family
- You want to know if there are certain nutrients your body requires more of
- You are interested in a genetic methylation test from Australia
- You want to personalise your health protocol specifically to your genetics
Is this the best methylation test in Australia?
Yes, Melbourne Functional Medicine offers one of the most comprehensive genetic methylation tests available in Australia.
This test analyses key genes involved in the methylation process, including MTHFR, COMT, AHCY, MTRR, CBS, MTR, PEMT, and MTHFD1. This gives you a detailed understanding of your methylation status and any genetic variations that may affect your health.
What sets accessing this test via our clinic apart is that we focus on actionable insights, not just identifying genetic risks. We consider how lifestyle and environmental factors can influence gene expression. By understanding your genetic methylation profile, we help you make informed decisions about diet, lifestyle, and supplements to support your health and reduce the risk of chronic conditions.
We provide personalised support throughout the process. We help you get your test kit, interpret your results, and develop a plan to address any methylation inefficiencies. This way, you not only get your genetic information but also understand how to use it to improve your health.
Compared to other providers in Australia, our test covers a broader range of genetic markers and combines it with personalised guidance. For anyone looking to gain deeper insights into their methylation status and take proactive steps for better health, our genetic methylation test is one of the most comprehensive options available.
How do I test for methylation?
A myDNA test ordered via our practitioners, covers numerous SNPs related to your methylation efficiency and if you may need practive support to help your body with this important function. It will give you results for your MTHFR genetic status as well ask other key SNPs related to methylation.
It involves a simple cheek swab.
How long do test results take to come back?
Results are usually back within 5-6 weeks of the lab receiving the test sample. We’ll notify you when your results are back.
Does this report tell me which diseases I am at a higher risk for?
The myDNA Comprehensive Health Report does not focus on disease statistics based on SNPs. Rather, the analysis gives you an understanding of how nutritional deficiency or toxicity may play a role in affecting your gene function and hence the root causes of certain health disorders may run in your family, and what you can actively do to decrease the probability of disease through the epigenetic application of diet, lifestyle and exercise.
What is the list of genes and SNPs in this methylation test
This test is exceptional value with a significant number of genes tested beyond methylation for a 360 view of your nutrigenomic profile:
5-HT2A
9p21
ABCG2 (Q141K)
ACAT1-02
ACE1 G2350A
ACE2 A8790G
ACSL1
ACTN3
ADD1
ADIPOQ
ADRB2
AGTR1
ALDH2
ANKK1
APB1
APOA2
APOE
ARMS2
ATM D1853N
BCMO1 A379V
BCMO1 R267S
BDNF
CAT C-262T
CBS
CBS 191150T
CBS A13637G
CFH
COL1A1
COMT
COQ2
CTH
CYP1A1
CYP1A2
CYP1B1*6 L432V
CYP2C19*17
CYP2C9*3 A1075C
CYP2D6 T100C
CYP2E1
CYP2R1
CYP3A4*1B
DAO C2029G
DHFR A20965G
DHFR C19483A
DI01
DI02
ESR2
F5
FAAH
FADS1
FADS2
FTO
FUT2
GAD1
GATA3
GPX1
GSTM1
GSTP1 C341T
GSTP1 I105V
HFE-C282Y
HLA DQ2.5
HLA-DQ8
HNMT
HNMT C314T
IL6
LCT
LPA
LZTFL1
MAO-A
MDM2
MLH1
MTHFD1 G1958A
MTHFR 1298
MTHFR 677
MTNR1B
MTR A2756G
MTRR A66G
NAT2
NBPF3
NOS1
NOS2
PEMT
PON1
PPAR-alpha
PPARGC1A
PPCDC
SELENBP1
SHBG
SIRT1
SLC17A7
SLC23A1
SOD2
SOD3
TCF7L2
TCN2 C766G
TFR2
TMPRSS2
TP53
VKORC1*2
XRCC3
Where can I get a genetic methylation test?
If you are based anywhere in Australia our team at Melbourne Functional Medicine can support you with getting a test kit for a genetic methylation test.
Just email or call our clinic and we will ensure this test is right for you and support you through the process: [email protected] or 1300 614 814.
Should I retest?
No. You do not need to test your genes more than once for genetic methylation SNPs. You can however, test your epigenetics if you wish to see how your genes are expressing and a Comprehensive Blood (and metabolite) Panel can be helpful to show you if your interventions are helping address any genetic methylation inefficiencies.
I've already completed this test. Can you help interpret the results?
Yes. Our practitioners provide comprehensive interpretation of your test results and help you translate them into clear, actionable steps – ensuring your health protocols are purposeful, personalised, and guided by real data. Book a test interpretation session here.

Mighty methylation: What it means for your healthspan
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