8 things I’ve learned about biohacking for women

Most biohacking advice is based on men. In this article, Health Coach Liv shares 8 powerful insights every woman should know to train smarter, fuel better, and recover fully – based on physiology, not guesswork.

A brain-derived peptide that suppresses appetite without nausea

A newly identified brain-derived peptide, BRP, significantly reduces appetite and body weight in mice and pigs without causing nausea. This breakthrough uncovers a non-incretin pathway for appetite control, offering a promising, targeted approach for managing obesity and enhancing metabolic health.

Targeting NF-κB p65 to extend healthspan

Lowering of NF-κB p65 protein in the liver appears to be a common biological effect across a wide range of anti-ageing strategies, including dietary, pharmaceutical, and genetic interventions, highlighting this inflammatory regulator as a potential unifying target for promoting longevity and metabolic resilience.

Could Akkermansia muciniphila extend your healthspan

Genetic evidence links specific gut bacteria, especially Akkermansia muciniphila, to traits of healthy ageing. This microbe may enhance lifespan and physical function by influencing inflammation and metabolism, suggesting gut microbiota as a potential target for promoting longevity and delaying age-related decline.

What aged organ transplants reveal about accelerated ageing

Transplanting older organs into younger recipients accelerates physical and cognitive decline by spreading cellular senescence, driven by factors like mitochondrial DNA. Treating donor organs with senolytics before transplantation reduces this impact, offering a promising strategy to improve health outcomes.

What steep survival curves mean for your healthspan

Some longevity interventions compress the time spent in poor health by steepening the survival curve. These steepening strategies – unlike those that merely extend lifespan – can reduce relative sickspan, offering a route to longer and healthier lives.

Linking gut diversity and nutrient loss in Parkinson’s

Changes in gut bacteria in Parkinson’s disease are associated with lower production of key nutrients and anti-inflammatory compounds, suggesting gut-targeted strategies may help support brain health and slow disease progression.