Aminoglycoside antibiotics, such as streptomycin, can inhibit TRP channels, disrupting calcium signalling essential for muscle and adipose tissue development. This interference may impair metabolic balance, potentially affecting healthspan and longevity.
Navigating the festive season: 6 ways to protect your health gains
The festive season doesn’t have to derail your health goals. With mindful strategies like stress management, enjoying treats without guilt, staying active, and prioritising rest, you can maintain balance and vitality. Discover practical tips to navigate the holidays with ease and enjoy the moments that matter most.
Geographic variation in life expectancy across Anglophone nations
Australia leads in life expectancy among high-income Anglophone nations, outperforming in reducing premature mortality from cardiovascular, respiratory, and external causes. It also exhibits lower geographic inequality in mortality, while the USA lags significantly, highlighting disparities and the importance of effective health policies for ageing populations.
Microplastics found in the brain and their impact on ageing
Researchers detected microplastics in human brain tissue using pyrolysis gas chromatography-mass spectrometry, indicating potential bioaccumulation. This finding raises concerns about microplastics’ impact on neurological health and ageing.
Dietary acid reduction as a pathway to healthy ageing
Reducing dietary acid through increased intake of fruits and vegetables or sodium bicarbonate supplementation slows chronic kidney disease progression, lowers systolic blood pressure, and improves cardiovascular health.
Healthspan vs lifespan: What’s the difference?
Discover the difference between living long and living well! Mark’s blog dives into healthspan vs lifespan, explains why biological age matters, and shares how small, impactful lifestyle changes can help you stay healthier for longer.
The role of mTORC1/2 in safeguarding ovarian function
Inhibiting mTORC1/2 during chemotherapy helps preserve ovarian function and fertility in mice, offering a potential approach to reducing chemotherapy-induced reproductive ageing and supporting healthspan.
Preserving cognitive function through improved lymphatic drainage
Restoring cervical lymphatic vessel function in ageing improves brain drainage, reduces inflammation, and enhances cognitive function. This approach could counter age-related cognitive decline, supporting healthier ageing and potentially extending healthspan.
A humanised mouse model reveals pathways to enhance longevity
A humanised mouse model now produces mature, class-switched, and hypermutated antibodies, offering insights into immune responses and advancing vaccine and antibody therapy research. This model may accelerate immunity understanding, supporting healthspan and longevity research.
Slowing brain ageing through region-specific Alzheimer’s insights
Single-cell analysis maps Alzheimer’s progression across brain regions, revealing specific cellular and molecular changes. The findings suggest targeted interventions could address Alzheimer’s-related dysfunction, potentially slowing progression and preserving brain health.