Celebrate Men’s Health Week by taking charge of your health at every age. From your 30s to your 90s, discover proactive, data-driven strategies to extend your healthspan, prevent disease, and optimise wellbeing through each decade of life.
AP2A1 reveals new targets for healthy ageing
Reducing AP2A1 levels in aged human cells rejuvenates them by shrinking cell size, softening structural fibres, restoring mobility, and lowering senescence signals.
Restoring the brain’s sugar shield boosts memory
Ageing disrupts a key sugar-protein layer called the glycocalyx lining brain blood vessels, weakening the blood–brain barrier and increasing brain inflammation and cognitive decline; restoring this layer in mice improves brain health and memory.
Autophagy, mitochondria and mTOR: sulforaphane’s secret to healthy ageing
Sulforaphane triggers fasting-like responses in human cells, enhancing mitochondrial function, autophagy, and nutrient-sensing pathways, while suppressing glucose uptake and mTOR signalling—mimicking the benefits of caloric restriction.
How trauma during pregnancy shapes future generations
Violence experienced by Syrian refugee women during pregnancy leaves biological marks on future generations, altering DNA methylation and accelerating biological ageing in children. These findings reveal an intergenerational epigenetic signature of trauma, with potential long-term impacts on healthspan and resilience across generations.
Can feeling thankful help you live longer?
Experiencing greater gratitude was linked with lower risk of death over three years in nearly 50,000 older women, suggesting it may support healthier ageing and longer life.
Healthspan: Redefining how we approach health and longevity
Healthspan is about living not just longer, but better, full of vitality, energy, and freedom from chronic illness. By uncovering root causes, embracing personalised habits, and shifting from survival mode to thriving, you can build a healthier, more vibrant future
Why midlife is the sweet spot for heart health
Structured high- and moderate-intensity exercise over two years reversed heart stiffening in previously sedentary middle-aged adults, improving cardiovascular fitness and potentially reducing future heart failure risk, showing it’s never too late to start exercising.
Cancer cells hijack immune mitochondria and disarm tumour defences
Cancer cells transfer damaged mitochondria into immune cells, causing dysfunction and early ageing in T cells, weakening the body’s natural defence against tumours.
How ageing drives cancer across the lifespan
Aging and cancer are deeply interconnected, influencing one another across the lifespan through immune decline, tissue changes, and cumulative environmental exposures, urging age-tailored approaches to cancer prevention, treatment, and research.
