Some longevity interventions compress the time spent in poor health by steepening the survival curve. These steepening strategies – unlike those that merely extend lifespan – can reduce relative sickspan, offering a route to longer and healthier lives.
Slower biological ageing linked to daily multivitamins
Daily multivitamin use slowed biological ageing by 10–20% over two years in older adults, as measured by advanced epigenetic clocks, suggesting a promising strategy to support healthy ageing when combined with good nutrition and lifestyle habits
Optimise your oral microbiome: Habits, products, breathing and more
Your oral microbiome does far more than protect your teeth – it influences immunity, inflammation, and whole-body health. Learn how to optimise it through smarter habits, better product choices, nasal breathing, and targeted strategies to reshape this vital ecosystem.
Restoring senescent cells with sound waves
Low-frequency ultrasound restores the function and growth of senescent cells by reversing ageing markers, enhancing cellular vitality, and extending healthspan and lifespan in mice, offering a non-invasive route to rejuvenation.
Torpor-like states reduce biological age in mice
Inducing a torpor-like state in mice significantly slowed blood epigenetic ageing and improved healthspan, revealing that a sustained drop in core body temperature, not calorie restriction or metabolic rate, is key to decelerating molecular ageing and promoting vitality.
AP2A1 reveals new targets for healthy ageing
Reducing AP2A1 levels in aged human cells rejuvenates them by shrinking cell size, softening structural fibres, restoring mobility, and lowering senescence signals.
Autophagy, mitochondria and mTOR: sulforaphane’s secret to healthy ageing
Sulforaphane triggers fasting-like responses in human cells, enhancing mitochondrial function, autophagy, and nutrient-sensing pathways, while suppressing glucose uptake and mTOR signalling—mimicking the benefits of caloric restriction.
How trauma during pregnancy shapes future generations
Violence experienced by Syrian refugee women during pregnancy leaves biological marks on future generations, altering DNA methylation and accelerating biological ageing in children. These findings reveal an intergenerational epigenetic signature of trauma, with potential long-term impacts on healthspan and resilience across generations.
Healthspan: Redefining how we approach health and longevity
Healthspan is about living not just longer, but better, full of vitality, energy, and freedom from chronic illness. By uncovering root causes, embracing personalised habits, and shifting from survival mode to thriving, you can build a healthier, more vibrant future
How ageing drives cancer across the lifespan
Aging and cancer are deeply interconnected, influencing one another across the lifespan through immune decline, tissue changes, and cumulative environmental exposures, urging age-tailored approaches to cancer prevention, treatment, and research.
