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Biological age influences epigenetic ageing in human blood cells

Apr 19, 2024

Epigenetic ageing of human blood cells corresponds with the biological age of the individual, indicating that blood cells age in sync with the body’s overall ageing process.

March 2024 – Aging Cell


Key takeaways


  • Epigenetic ageing in human blood cells aligns with biological age: This suggests that the ageing of blood cells is more reflective of an individual’s physiological condition and health rather than their chronological years, highlighting a potential target for ageing research
  • Variability in blood cell ageing: The rate at which blood cells age differs based on the general ageing dynamics of the individual. This variability could be important for developing personalised ageing interventions
  • Insights from epigenetic markers in blood cells: By studying these markers, scientists can gain valuable information about the biological ageing process. This could help in predicting age-related diseases earlier and more accurately


Understanding how blood cells age provides a foundation for researching methods to decelerate or modify the biological ageing process, which could result in healthier, longer lifespans.


Read the article at: Holland, Petter, et al. “Epigenetic Aging of Human Blood Cells Is Influenced by the Age of the Host Body.” Aging Cell, p. e14112,