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Reversing age with stress recovery

Biological age is dynamic and can rapidly change in response to stress, as observed in young mice and humans. Stress increases biological age, but this effect can be reversed upon recovery. This phenomenon is evident at epigenetic, transcriptomic, and metabolomic...

The link between gut health and ageing acceleration

Gut bacteria may causally influence biological ageing by altering DNA methylation, with implications for microbiota-focused longevity therapies. November 2023 - Scientific Reports   Key takeaways   Gut microbiota's causal role: The diversity and presence of...

Porcine plasma and longevity breakthrough

Injecting aged rats with a young porcine plasma fraction significantly reversed molecular ageing in multiple organs, halving the biological age of blood, heart, and liver tissues, and enhancing organ functionality, indicating promising rejuvenation therapy potential....

New DNA clock measures mammalian ageing

A universal DNA methylation-based clock accurately estimates age across different mammalian tissues, aiding ageing research and the pursuit of longevity interventions. August 2023 - Nature Aging   Key takeaways Refined accuracy of universal DNA methylation clock:...

Redefining age: Insights from the PCAge clock

The PCAge clinical ageing clock identifies healthy and unhealthy ageing patterns. Using ACE-Is or ARBs reduces mortality risk and slows biological age acceleration, offering a proactive approach to ageing and age-related diseases.   Key takeaways: The principal...

How excess weight fast-forwards your biological clock

Being overweight is causally linked to accelerated ageing, evidenced by shorter telomeres, increased frailty, and more pronounced facial ageing. These findings highlight the significance of weight management in countering the effects of rapid ageing.   Key...

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