Daily activities, including sleep, physical activity, and sedentary behavior, interact within a 24-hour period, impacting sleep quality among Australian children and adults. Using compositional data analysis, the research emphasises the importance of considering the...
How blood metabolites can reveal your true age
A new molecular index based on blood metabolites can measure biological age, which may reflect health better than chronological age. This index helps distinguish between individuals ageing at different rates and suggests that lifestyle changes could potentially...
Vitamin A regulates lineage plasticity to guide stem cell differentiation choices
Vitamin A, via its metabolite all-trans retinoic acid (atRA), controls stem cell differentiation by resolving lineage plasticity. This process is essential for proper tissue repair and maintaining correct cell lineages in the skin, including hair follicles and...
Benefits of ergothioneine for longevity and healthy ageing in male mice
Ergothioneine, a dietary supplement, effectively increases lifespan and reduces age-related declines in physical and cognitive functions in male mice. Regular intake shows promise in promoting longevity and mitigating the effects of ageing. March 2024 - GeroScience...
Biological age influences epigenetic ageing in human blood cells
Epigenetic ageing of human blood cells corresponds with the biological age of the individual, indicating that blood cells age in sync with the body's overall ageing process. March 2024 - Aging Cell Key takeaways Epigenetic ageing in human blood cells...
Mitochondrial dysfunction influences brain ageing and disease
Mitochondrial dysfunction is highlighted as a pivotal element in brain ageing and associated diseases, playing a significant role in energy shortages, elevated oxidative stress, and neuronal harm, driving the advancement of neurodegenerative conditions. March 2024 -...
The science of fasting for healthier ageing
The study reveals that a 7-day complete caloric restriction triggers significant multi-organ proteome changes in humans, suggesting potential benefits for longevity and aging. March 2024 - Nature Metabolism Key takeaways Caloric restriction for 7 days...
Sleep enhances brain health and longevity
Neuronal activity boosts cerebrospinal fluid flow to remove brain waste during sleep, potentially affecting longevity and ageing. February 2024 - Nature Key takeaways Neuronal activity enhances fluid flow: The brain's neurons, when active, drive the flow...
Functional medicine health coaching improves diet compliance and health outcomes
Functional medicine health coaching significantly enhances adherence to elimination diets and improves self-reported health outcomes, as demonstrated in a randomised controlled trial. February 2024 - Medicine Key takeaways Enhanced dietary adherence:...
CST–polymerase crucial for the complete replication of telomeres
The CST–polymerase α-primase complex plays a key role in cellular ageing and longevity by ensuring the complete replication of chromosome ends, offering potential insights for ageing-related therapies. February 2024 - Nature Key takeaways Crucial role of...
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