How GLTD impacts aging and age-related diseases like Alzheimer’s

Gene-length-dependent transcription decline (GLTD) in ageing organisms results in longer genes showing decreased expression. This decline, linked to DNA damage and polymerase stalling, contributes to ageing and age-related diseases like Alzheimer's. Targeting GLTD...

Preventing menopause indefinitely through ovarian tissue freezing

Ovarian tissue freezing could delay or prevent menopause indefinitely by preserving fertility and hormonal function. This involves freezing and re-implanting ovarian tissue, extending reproductive lifespan and mitigating menopause-related ageing effects. January 2024...

The benefits of balanced daily routines on sleep patterns and ageing

Daily activities, including sleep, physical activity, and sedentary behavior, interact within a 24-hour period, impacting sleep quality among Australian children and adults. Using compositional data analysis, the research emphasises the importance of considering the...

How blood metabolites can reveal your true age

A new molecular index based on blood metabolites can measure biological age, which may reflect health better than chronological age. This index helps distinguish between individuals ageing at different rates and suggests that lifestyle changes could potentially...

Biological age influences epigenetic ageing in human blood cells

Epigenetic ageing of human blood cells corresponds with the biological age of the individual, indicating that blood cells age in sync with the body's overall ageing process. March 2024 - Aging Cell   Key takeaways   Epigenetic ageing in human blood cells...

Mitochondrial dysfunction influences brain ageing and disease

Mitochondrial dysfunction is highlighted as a pivotal element in brain ageing and associated diseases, playing a significant role in energy shortages, elevated oxidative stress, and neuronal harm, driving the advancement of neurodegenerative conditions. March 2024 -...