Greater exposure to neighbourhood green space is initially linked to longer telomeres, indicating potential health benefits. However, this association diminishes when considering additional factors like air pollution and neighbourhood deprivation, underscoring the...
Astaxanthin and meclizine extend lifespan in male mice
Astaxanthin and meclizine extended male mouse lifespans by 12% and 8%, respectively, when started at 12 months of age. However, they had no significant effect on female mice. Other tested compounds, including fisetin and dimethyl fumarate, showed no notable impact on...
How FOXO3 influences vascular ageing
FOXO3, a gene associated with exceptional human longevity, plays a critical role in regulating vascular ageing and is implicated in various ageing-related vascular diseases. Polymorphisms in FOXO3 are linked to reduced cardiovascular disease morbidity in long-lived...
ApoE4 influence on Alzheimer’s progression
The ApoE4 gene variant may accelerate tau pathology at lower amyloid levels in Alzheimer's disease, influencing disease progression and treatment strategies. November 2023 - JAMA Neurology Key takeaways ApoE4 and tau pathology: Individuals carrying the...
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