Rapamycin, an mTOR inhibitor, holds untapped potential for extending life and improving health. Despite its promise in anti-ageing, societal and scientific challenges have slowed its adoption in longevity treatments. October 2019 - Aging Key takeaways ...
Reversing age with platelet factors
Young blood plasma and platelet factors show promise in altering gene expression to boost immune function and nervous system health, potentially reversing cognitive decline associated with ageing. August 2023 - Nature Key takeaways Gene expression...
Thymus removal’s impact on ageing
Adults who have their thymus removed face higher risks of death, cancer, and autoimmune diseases. This is linked to a decrease in new T-cell production and an increase in proinflammatory cytokines, underscoring the vital role of the adult thymus in maintaining immune...
Strengthening immunity with short-term fasting
Dietary restriction enhances T cell immunity, balancing homeostasis and reducing inflammation. While long-term fasting weakens T cell response due to increased autophagy and apoptosis, short-term restriction boosts T cell function. July 2023 - Cellular and Molecular...
How stress affects ageing: Insights from a new study
New research reveals that physiological stress load may accelerate ageing by affecting immune cells. The study found that stress load correlates with age and is linked to changes in T lymphocyte subsets, which are crucial for immune response. This suggests that...
Exploring the checkered past of rapamycin: a breakthrough in anti-aging research
This article discusses the interesting story of a drug called rapamycin, which has shown potential as an anti-ageing treatment. Rapamycin was accidentally discovered on Easter Island in the 1970s while scientists were studying soil samples. Originally, it was used as...
Immunosenescence: Investigating molecular mechanisms and their impact on diseases
Immunosenescence, the age-related decline in immune function, is associated with increased susceptibility to infections, reduced effectiveness of vaccinations, earlier onset of age-related diseases, and the development of neoplasms. Ageing organisms exhibit a chronic...
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