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Research

The latest insights on health and longevity

Reversing age with stress recovery

Biological age is dynamic and can rapidly change in response to stress, as observed in young mice and humans. Stress increases biological age, but this effect can be reversed upon recovery. This phenomenon is evident at epigenetic, transcriptomic,...

Breakthrough in cancer treatment: Molecular jackhammers

Molecular jackhammers activate vibronic modes in single molecules, efficiently destroying cancer cells by mechanically disassembling their membranes, offering a potential alternative to traditional cancer therapies with fewer side effects. December...

Tackling age-related dental issues with RvE1

Resolvin E1 (RvE1) shows promise in dental pulp regeneration, enhancing Axin2-expressing cell proliferation and differentiation. It modulates inflammation, reduces infection severity, and prevents apical periodontitis, offering a new treatment...

Cell therapy’s impact on heart health

Cell therapy significantly improves the quality of life in patients with ischemic heart failure. This is particularly evident in those with advanced left ventricular enlargement, as measured by the Minnesota Living with Heart Failure Questionnaire....

Nutmeg compound extends lifespan of fruit flies

Nectandrin B, a compound derived from nutmeg, has been found to significantly extend the lifespan of fruit flies by up to 42.6%. This increase in lifespan is also associated with improvements in various age-related conditions, including locomotive...

The relationship between green space exposure and longevity

Greater exposure to neighbourhood green space is initially linked to longer telomeres, indicating potential health benefits. However, this association diminishes when considering additional factors like air pollution and neighbourhood deprivation,...

Carrot compound isofalcarintriol enhances longevity

Isofalcarintriol, a polyacetylene found in carrots, promotes health and delays ageing. It activates defense mechanisms against oxidative stress, extends lifespan in worms, and in mice, improves glucose metabolism, enhances exercise capacity, and...

Fisetin supplementation for cellular senescence reduction

Fisetin, a natural compound, has been found to improve arterial function in old mice by reducing cellular senescence. This was achieved through intermittent dosing, which led to enhanced endothelial function and decreased arterial stiffness. The...